A meta-analysis comparing the diagnostic performance of abbreviated MRI and a full diagnostic protocol in breast cancer

•The diagnostic performance of abbreviated MRI matches standard breast MRI. •Few studies investigated screening populations alone. mean examination time is significantly reduced. protocols reported are very varied. AIM To undertake a meta-analysis the (ABB) magnetic resonance imaging (MRI) and full protocol (FDP-MRI) in cancer. MATERIALS AND METHODS This was performed using Preferred Reporting Items for Systematic Reviews Meta-Analysis Diagnostic Test Accuracy (PRISMA-DTA) guidelines. The PubMed EMBASE databases were searched through August 2019 comparing ABB-MRI FDP-MRI breast. Studies reviewed by two authors independently according to eligibility exclusion criteria split into subgroups (screening population cohorts enriched with known cancers) avoid bias. Quality assessment bias accuracy determined Assessment Studies-2 (QUADAS-2). each subgroup pooled bivariate random effects model summary receiver operating characteristic (sROC) curves produced. Sensitivities specificities compared paired t-test. RESULTS Five (62/2,588 cancers/patients) eight cohort (540/1,432 included meta-analysis. QUADAS-2 showed low risk most studies. sensitivity/specificity/area under curve (AUC) 0.90/0.92/0.94 0.92/0.95/0.97 FDP-MRI. sensitivity/specificity/AUC 0.93/0.83/0.94 0.93/0.84/0.95 There no significant difference sensitivity or specificity (p=0.18 0.27, p=0.18 0.93, respectively). CONCLUSION performances used either comparable. large variation patient population, study methodology, reported.